Paulista Avenue
Paulista Avenue (Avenida Paulista) is one of São Paulo's most popular postcards, as it is the pride of Paulistanos. It is one of the largest business centers, and probably the largest cultural region in the city.
The avenue and its surroundings, such as Rua Augusta and Alameda Santos, contain numerous shop galleries, art galleries, theatres, movie theaters, pubs, hotel, coffe shops, bookstores, and gourmet restaurants. Gay nightlife is intense on Consolacao and Haddock Lobo Streets.
To get to Avenida Paulista, take the subway to Brigadeiro, Trianon-Masp (museum), or Consolação stations. The station closest to nightlife venues though is the Consolação one with exits on both Ruas Augusta and da Consolacao. By car, traffic is often intense and parking expensive.

Museums
As the art center of the country, São Paulo offers museums in a variety of subjects. Check each region section of this guide for a list of museums.

Buildings with observation decks
São Paulo is a beautiful city seen from above, so spare some time to go to one of the few points where you'll be able to see how far this city extends to, specially at sunset.
-Banespa Tower, Rua João Brícola, 24, Centro. São Bento Metrô station, ? +55(11) 3249-7180. M-F, 10AM-5PM. The observation deck is on the 34th floor, 160 m above ground. For many decades, it used to be the highest building in town. There is a small museum on the top of the building." Make sure and bring ID (passport) because it is required for entrance. Free entrance. 
-Restaurant Skye, Hotel Unique, Avenida Brigadeiro Luiz Antônio, 4700. On the rooftop of posh Hotel Unique, Skye serves excellent fusion food under the supervision of chef Emmanuel Bassoleil. Good for night views of the area around Ibirapuera Park. Free entrance.  edit
-São Paulo Jockey Club, Av. Lineu de Paula Machado, 1263. There are two bars and a couple of posh restaurants with a great view of the River Pinheiros, especially around 6PM, when you can go straight from work or a busy day walking about to watch the sun set above town. Free entrance.

Theaters
São Paulo has a great number of theaters, most of which feature plays in Portuguese. The British Cultural Centre, Goethe Institut, Instituto Cervantes and Alliance Française occasionally have plays in English, German, Spanish and French, respectively.